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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCC
All Species:
45.45
Human Site:
S277
Identified Species:
76.92
UniProt:
Q15814
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15814
NP_003183.1
346
39220
S277
R
I
F
L
Q
V
T
S
R
A
I
V
E
D
C
Chimpanzee
Pan troglodytes
XP_518477
346
39236
S277
R
I
F
L
Q
V
T
S
R
A
I
V
E
D
C
Rhesus Macaque
Macaca mulatta
XP_001088723
346
39322
S277
R
V
F
L
Q
V
T
S
R
A
I
V
E
D
C
Dog
Lupus familis
XP_538923
388
42549
S319
R
I
F
L
Q
V
T
S
R
A
I
V
E
D
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCN9
341
38106
S272
R
V
F
L
Q
V
T
S
R
A
I
V
E
D
C
Rat
Rattus norvegicus
NP_001101670
340
38058
S271
R
I
F
L
Q
V
T
S
R
A
I
V
E
D
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508991
335
37102
S266
R
I
Y
L
Q
V
T
S
R
A
V
I
E
D
C
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922489
350
39443
S272
R
V
Y
L
H
V
T
S
R
A
I
I
E
D
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722959
355
40503
C262
R
I
Y
M
H
V
T
C
R
A
I
I
E
D
C
Honey Bee
Apis mellifera
XP_001120828
342
39209
S273
T
I
Y
I
H
V
T
S
R
S
I
I
E
D
C
Nematode Worm
Caenorhab. elegans
Q27249
256
29613
Q196
R
E
D
S
Y
E
E
Q
I
R
T
V
S
S
R
Sea Urchin
Strong. purpuratus
XP_783718
353
39965
S284
K
F
Y
L
H
V
T
S
R
A
I
I
E
D
T
Poplar Tree
Populus trichocarpa
XP_002307082
324
36492
S255
D
F
Y
L
R
V
R
S
R
P
I
I
E
D
C
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_195702
345
38291
S272
D
F
Y
L
R
V
R
S
R
P
I
I
E
D
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.3
72.9
N.A.
76
74.5
N.A.
61.5
N.A.
N.A.
43.7
N.A.
33.5
38.7
21.1
39.6
Protein Similarity:
100
99.1
97.6
78.3
N.A.
84.3
83.5
N.A.
74.5
N.A.
N.A.
64
N.A.
57.7
58
40.1
62.6
P-Site Identity:
100
100
93.3
100
N.A.
93.3
100
N.A.
80
N.A.
N.A.
73.3
N.A.
66.6
60
13.3
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
N.A.
N.A.
93.3
N.A.
86.6
86.6
13.3
80
Percent
Protein Identity:
29.7
N.A.
N.A.
32.3
N.A.
N.A.
Protein Similarity:
48.2
N.A.
N.A.
51.7
N.A.
N.A.
P-Site Identity:
53.3
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
73.3
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
72
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
79
% C
% Asp:
15
0
8
0
0
0
0
0
0
0
0
0
0
93
0
% D
% Glu:
0
8
0
0
0
8
8
0
0
0
0
0
93
0
0
% E
% Phe:
0
22
43
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
29
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
50
0
8
0
0
0
0
8
0
86
50
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
79
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% P
% Gln:
0
0
0
0
50
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
72
0
0
0
15
0
15
0
93
8
0
0
0
0
8
% R
% Ser:
0
0
0
8
0
0
0
86
0
8
0
0
8
8
8
% S
% Thr:
8
0
0
0
0
0
79
0
0
0
8
0
0
0
8
% T
% Val:
0
22
0
0
0
93
0
0
0
0
8
50
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
50
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _